Insight into microtubule nucleation from tubulin-capping proteins

Nucleation is one of the least understood steps of microtubule dynamics. It is a kinetically unfavorable process that is templated in the cell by the γ-tubulin ring complex or by preexisting microtubules; it also occurs in vitro from pure tubulin. Here we study the nucleation inhibition potency of n...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Campanacci, Valérie, Urvoas, Agathe, Cantos-Fernandes, Soraya, Aumont-Nicaise, Magali, Arteni, Ana-Andreea, Velours, Christophe, Valerio-Lepiniec, Marie, Dreier, Birgit, Plückthun, Andreas, Pilon, Antoine, Poüs, Christian, Minard, Philippe, Gigant, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525497/
https://ncbi.nlm.nih.gov/pubmed/31036638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813559116
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