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Selection and Characterization of Artificial Proteins Targeting the Tubulin α Subunit

Microtubules are cytoskeletal filaments of eukaryotic cells made of αβ-tubulin heterodimers. Structural studies of non-microtubular tubulin rely mainly on molecules that prevent its self-assembly and are used as crystallization chaperones. Here we identified artificial proteins from an αRep library...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Campanacci, Valérie, Urvoas, Agathe, Consolati, Tanja, Cantos-Fernandes, Soraya, Aumont-Nicaise, Magali, Valerio-Lepiniec, Marie, Surrey, Thomas, Minard, Philippe, Gigant, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408325/
https://ncbi.nlm.nih.gov/pubmed/30661854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.12.001
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