Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States

During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data in 2iL/I/F naive cells demonstrate that a subs...

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Publicado en:Stem Cell Reports
Main Authors: Battle, Stephanie L., Doni Jayavelu, Naresh, Azad, Robert N., Hesson, Jennifer, Ahmed, Faria N., Overbey, Eliah G., Zoller, Joseph A., Mathieu, Julie, Ruohola-Baker, Hannele, Ware, Carol B., Hawkins, R. David
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524944/
https://ncbi.nlm.nih.gov/pubmed/31056477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.004
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