Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States

During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data in 2iL/I/F naive cells demonstrate that a subs...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Battle, Stephanie L., Doni Jayavelu, Naresh, Azad, Robert N., Hesson, Jennifer, Ahmed, Faria N., Overbey, Eliah G., Zoller, Joseph A., Mathieu, Julie, Ruohola-Baker, Hannele, Ware, Carol B., Hawkins, R. David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524944/
https://ncbi.nlm.nih.gov/pubmed/31056477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.004
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