Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States

During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data in 2iL/I/F naive cells demonstrate that a subs...

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Udgivet i:Stem Cell Reports
Main Authors: Battle, Stephanie L., Doni Jayavelu, Naresh, Azad, Robert N., Hesson, Jennifer, Ahmed, Faria N., Overbey, Eliah G., Zoller, Joseph A., Mathieu, Julie, Ruohola-Baker, Hannele, Ware, Carol B., Hawkins, R. David
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524944/
https://ncbi.nlm.nih.gov/pubmed/31056477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.004
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