Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm

Most viruses are known to spontaneously generate defective viral genomes (DVG) due to errors during replication. These DVGs are subgenomic and contain deletions that render them unable to complete a full replication cycle in the absence of a co-infecting, non-defective helper virus. DVGs, especially...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Bosma, Trent J., Karagiannis, Konstantinos, Santana-Quintero, Luis, Ilyushina, Natalia, Zagorodnyaya, Tatiana, Petrovskaya, Svetlana, Laassri, Majid, Donnelly, Raymond P., Rubin, Steven, Simonyan, Vahan, Sauder, Christian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524942/
https://ncbi.nlm.nih.gov/pubmed/31100083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216944
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi