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Deep Sequencing for Evaluation of Genetic Stability of Influenza A/California/07/2009 (H1N1) Vaccine Viruses

Virus growth during influenza vaccine manufacture can lead to mutations that alter antigenic properties of the virus, and thus may affect protective potency of the vaccine. Different reassortants of pandemic "swine" H1N1 influenza A vaccine (121XP, X-179A and X-181) viruses as well as wild...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Majid, Laassri, Zagorodnyaya, Tatiana, Plant, Ewan P., Petrovskaya, Svetlana, Bidzhieva, Bella, Ye, Zhiping, Simonyan, Vahan, Chumakov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583247/
https://ncbi.nlm.nih.gov/pubmed/26407068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138650
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