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Microarray Hybridization for Assessment of the Genetic Stability of Chimeric West Nile/Dengue 4 Virus

Genetic stability is an important characteristic of live viral vaccines because an accumulation of mutants can cause reversion to a virulent phenotype as well as a loss of immunogenic properties. This study was aimed at evaluating the genetic stability of a live attenuated West Nile (WN) virus vacci...

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Bibliografiske detaljer
Main Authors: Laassri, Majid, Bidzhieva, Bella, Speicher, James, Pletnev, Alexander G., Chumakov, Konstantin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410669/
https://ncbi.nlm.nih.gov/pubmed/21360544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.22033
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