Genomic Analysis of Vaccine-Derived Poliovirus Strains in Stool Specimens by Combination of Full-Length PCR and Oligonucleotide Microarray Hybridization

Sabin strains of poliovirus used in the manufacture of oral poliovirus vaccine (OPV) are prone to genetic variations that occur during growth in cell cultures and the organisms of vaccine recipients. Such derivative viruses often have increased neurovirulence and transmissibility, and in some cases...

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Detalhes bibliográficos
Main Authors: Laassri, Majid, Dragunsky, Eugenia, Enterline, Joan, Eremeeva, Tatiana, Ivanova, Olga, Lottenbach, Kathleen, Belshe, Robert, Chumakov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151934/
https://ncbi.nlm.nih.gov/pubmed/15956413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.6.2886-2894.2005
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