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Genomic Analysis of Vaccine-Derived Poliovirus Strains in Stool Specimens by Combination of Full-Length PCR and Oligonucleotide Microarray Hybridization

Sabin strains of poliovirus used in the manufacture of oral poliovirus vaccine (OPV) are prone to genetic variations that occur during growth in cell cultures and the organisms of vaccine recipients. Such derivative viruses often have increased neurovirulence and transmissibility, and in some cases...

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Библиографические подробности
Главные авторы: Laassri, Majid, Dragunsky, Eugenia, Enterline, Joan, Eremeeva, Tatiana, Ivanova, Olga, Lottenbach, Kathleen, Belshe, Robert, Chumakov, Konstantin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151934/
https://ncbi.nlm.nih.gov/pubmed/15956413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.6.2886-2894.2005
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