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Separation and assembly of deep sequencing data into discrete sub-population genomes

Sequence heterogeneity is a common characteristic of RNA viruses that is often referred to as sub-populations or quasispecies. Traditional techniques used for assembly of short sequence reads produced by deep sequencing, such as de-novo assemblers, ignore the underlying diversity. Here, we introduce...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Karagiannis, Konstantinos, Simonyan, Vahan, Chumakov, Konstantin, Mazumder, Raja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737798/
https://ncbi.nlm.nih.gov/pubmed/28977510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx755
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