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Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency

Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation share common features; both involve undergoing a dramatic change in cell identit...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Ferreirós, Alba, Pedrosa, Pablo, Da Silva-Álvarez, Sabela, Triana-Martínez, Francisco, Vilas, Jéssica M., Picallos-Rabina, Pilar, González, Patricia, Gómez, María, Li, Han, García-Caballero, Tomás, González-Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524732/
https://ncbi.nlm.nih.gov/pubmed/31056476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.006
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