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Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency

Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation share common features; both involve undergoing a dramatic change in cell identit...

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Publicat a:Stem Cell Reports
Autors principals: Ferreirós, Alba, Pedrosa, Pablo, Da Silva-Álvarez, Sabela, Triana-Martínez, Francisco, Vilas, Jéssica M., Picallos-Rabina, Pilar, González, Patricia, Gómez, María, Li, Han, García-Caballero, Tomás, González-Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524732/
https://ncbi.nlm.nih.gov/pubmed/31056476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.006
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