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Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency

Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation share common features; both involve undergoing a dramatic change in cell identit...

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Detalles Bibliográficos
Publicado en:Stem Cell Reports
Main Authors: Ferreirós, Alba, Pedrosa, Pablo, Da Silva-Álvarez, Sabela, Triana-Martínez, Francisco, Vilas, Jéssica M., Picallos-Rabina, Pilar, González, Patricia, Gómez, María, Li, Han, García-Caballero, Tomás, González-Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524732/
https://ncbi.nlm.nih.gov/pubmed/31056476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.006
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