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Net charge of antibody complementarity-determining regions is a key predictor of specificity
Specificity is one of the most important and complex properties that is central to both natural antibody function and therapeutic antibody efficacy. However, it has proven extremely challenging to define robust guidelines for predicting antibody specificity. Here we evaluated the physicochemical det...
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| Vydáno v: | Protein Eng Des Sel |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6524611/ https://ncbi.nlm.nih.gov/pubmed/30770934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzz002 |
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