A T Cell Suppressive Circuitry Mediated by CD39 and Regulated by ShcC/Rai Is Induced in Astrocytes by Encephalitogenic T Cells

Multiple sclerosis is an autoimmune disease caused by autoreactive immune cell infiltration into the central nervous system leading to inflammation, demyelination, and neuronal loss. While myelin-reactive Th1 and Th17 are centrally implicated in multiple sclerosis pathogenesis, the local CNS microen...

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Udgivet i:Front Immunol
Main Authors: Ulivieri, Cristina, De Tommaso, Domiziana, Finetti, Francesca, Ortensi, Barbara, Pelicci, Giuliana, D'Elios, Mario Milco, Ballerini, Clara, Baldari, Cosima T.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524536/
https://ncbi.nlm.nih.gov/pubmed/31134091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01041
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