The Neuron-Specific Rai (ShcC) Adaptor Protein Inhibits Apoptosis by Coupling Ret to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway

Rai is a recently identified member of the family of Shc-like proteins, which are cytoplasmic signal transducers characterized by the unique PTB-CH1-SH2 modular organization. Rai expression is restricted to neuronal cells and regulates in vivo the number of postmitotic sympathetic neurons. We report...

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Autores principales: Pelicci, Giuliana, Troglio, Flavia, Bodini, Alessandra, Melillo, Rosa Marina, Pettirossi, Valentina, Coda, Laura, De Giuseppe, Antonio, Santoro, Massimo, Pelicci, Pier Giuseppe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC139827/
https://ncbi.nlm.nih.gov/pubmed/12242309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7351-7363.2002
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