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Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC
p66SHC is a pro-oxidant member of the SHC family of protein adaptors that acts as a negative regulator of cell survival. In lymphocytes p66SHC exploits both its adaptor and its reactive oxygen species (ROS)-elevating function to antagonize mitogenic and survival signaling and promote apoptosis. As a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020-03-01
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| Colecção: | Frontiers in Cell and Developmental Biology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/article/10.3389/fcell.2020.00193/full |
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