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γ-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo

We have shown previously that γ-glutamyl transpeptidase (GGT) activity is essential for the nephrotoxicity of cisplatin. In this study we asked whether GGT activity was necessary for the antitumor activity of cisplatin. GGT was transfected into PC3 cells, a human prostate tumor cell line. Two indepe...

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Bibliografske podrobnosti
izdano v:Carcinogenesis
Main Authors: Hanigan, Marie H., Gallagher, Betty C., Townsend, Danyelle M., Gabarra, Veronica
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522259/
https://ncbi.nlm.nih.gov/pubmed/10223181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/20.4.553
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