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γ-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo
We have shown previously that γ-glutamyl transpeptidase (GGT) activity is essential for the nephrotoxicity of cisplatin. In this study we asked whether GGT activity was necessary for the antitumor activity of cisplatin. GGT was transfected into PC3 cells, a human prostate tumor cell line. Two indepe...
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| Publicado no: | Carcinogenesis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522259/ https://ncbi.nlm.nih.gov/pubmed/10223181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/20.4.553 |
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