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Human germ cell tumours: expression of γ-glutamyl transpeptidase and sensitivity to cisplatin

Previous studies have shown that the enzyme γ-glutamyl transpeptidase (GGT) is essential for the nephrotoxicity of cisplatin. This study was designed to determine whether GGT activity is necessary for the therapeutic effect of the drug. The relationship between GGT expression and clinical response t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hanigan, M H, Frierson, H F, Abeler, V M, Kaern, J, Taylor, P T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374348/
https://ncbi.nlm.nih.gov/pubmed/10487615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690653
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