A Chemogenomic Screening Platform Used to Identify Chemotypes Perturbing HSP90 Pathways

Compounds that modulate the heat shock protein (HSP) network have potential in a broad range of research applications and diseases. A yeast-based liquid culture assay that measured time-dependent turbidity enabled the high-throughput screening of different Saccharomyces cerevisae strains to identify...

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Pubblicato in:SLAS Discov
Autori principali: Thomas, Fiona M., Goode, Kourtney M., Rajwa, Bartek, Bieberich, Andrew A., Avramova, Larisa V., Hazbun, Tony R., Jo Davisson, V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521697/
https://ncbi.nlm.nih.gov/pubmed/28346089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555216687525
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