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DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Autophagy can protect cancer cells from acute starvation and enhance resistance to chemotherapy. Previously, we reported that autophagy plays a critical role in the survival of dormant, drug resistant ovarian cancer cells using human xenograft models and correlated the up-regulation of autophagy and...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Sutton, Margie N., Huang, Gilbert Y., Liang, Xiaowen, Sharma, Rajesh, Reger, Albert S., Mao, Weiqun, Pang, Lan, Rask, Philip J., Lee, Kwangkook, Gray, Joshua P., Hurwitz, Amy M., Palzkill, Timothy, Millward, Steven W., Kim, Choel, Lu, Zhen, Bast, Robert C.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521623/
https://ncbi.nlm.nih.gov/pubmed/31003488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040557
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