DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Autophagy can protect cancer cells from acute starvation and enhance resistance to chemotherapy. Previously, we reported that autophagy plays a critical role in the survival of dormant, drug resistant ovarian cancer cells using human xenograft models and correlated the up-regulation of autophagy and...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Sutton, Margie N., Huang, Gilbert Y., Liang, Xiaowen, Sharma, Rajesh, Reger, Albert S., Mao, Weiqun, Pang, Lan, Rask, Philip J., Lee, Kwangkook, Gray, Joshua P., Hurwitz, Amy M., Palzkill, Timothy, Millward, Steven W., Kim, Choel, Lu, Zhen, Bast, Robert C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521623/
https://ncbi.nlm.nih.gov/pubmed/31003488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040557
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