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Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes

The potential anticancer effects of statins—a widely used class of cholesterol lowering drugs—has generated significant interest, as has the use of epigenetic modifying drugs such as HDAC and DNMT inhibitors. We set out to investigate the effect of statin drugs on epigenetic modifications in multipl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Bridgeman, Stephanie, Northrop, Wendy, Ellison, Gaewyn, Sabapathy, Thiru, Melton, Phillip E., Newsholme, Philip, Mamotte, Cyril D. S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521159/
https://ncbi.nlm.nih.gov/pubmed/30974899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040516
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