α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin

Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of astrocytes. We hypothesized that agonism on α7...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Cao, Mingju, MacDonald, James W., Liu, Hai L., Weaver, Molly, Cortes, Marina, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, André, Schulkin, Jay, Antonelli, Marta C., Bernier, Raphael A., Dorschner, Michael, Bammler, Theo K., Frasch, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520997/
https://ncbi.nlm.nih.gov/pubmed/31143190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01063
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker