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RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain

BACKGROUND: The chronically instrumented fetal sheep is a widely used animal model to study fetal brain development in health and disease, but no methods exist yet to interrogate dedicated brain cell populations to identify their molecular and genomic phenotype. For example, the molecular mechanisms...

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Detalhes bibliográficos
Publicado no:J Neurosci Methods
Main Authors: Cortes, M., Cao, M., Liu, H.L., Burns, P., Moore, C., Fecteau, G., Desrochers, A., Barreiro, L.B., Antel, J.P., Frasch, M.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359012/
https://ncbi.nlm.nih.gov/pubmed/27856275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2016.11.008
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