α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin

Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of astrocytes. We hypothesized that agonism on α7...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Cao, Mingju, MacDonald, James W., Liu, Hai L., Weaver, Molly, Cortes, Marina, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, André, Schulkin, Jay, Antonelli, Marta C., Bernier, Raphael A., Dorschner, Michael, Bammler, Theo K., Frasch, Martin G.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520997/
https://ncbi.nlm.nih.gov/pubmed/31143190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01063
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