α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin

Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of astrocytes. We hypothesized that agonism on α7...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Cao, Mingju, MacDonald, James W., Liu, Hai L., Weaver, Molly, Cortes, Marina, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, André, Schulkin, Jay, Antonelli, Marta C., Bernier, Raphael A., Dorschner, Michael, Bammler, Theo K., Frasch, Martin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520997/
https://ncbi.nlm.nih.gov/pubmed/31143190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01063
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