Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis

Autophagy is an intracellular catabolic system. It delivers cellular components to lysosomes for degradation and supplies nutrients that promote cell survival under stress conditions. Although much is known regarding starvation-induced autophagy, the regulation of autophagy by cellular energy level...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Che, Lixiao, Yang, Xingyuan, Ge, Chunmin, El-Amouri, Salim S., Wang, Qi-En, Pan, Dao, Herzog, Thomas J., Du, Chunying
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519829/
https://ncbi.nlm.nih.gov/pubmed/31091257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216553
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