Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis

Autophagy is an intracellular catabolic system. It delivers cellular components to lysosomes for degradation and supplies nutrients that promote cell survival under stress conditions. Although much is known regarding starvation-induced autophagy, the regulation of autophagy by cellular energy level...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Che, Lixiao, Yang, Xingyuan, Ge, Chunmin, El-Amouri, Salim S., Wang, Qi-En, Pan, Dao, Herzog, Thomas J., Du, Chunying
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519829/
https://ncbi.nlm.nih.gov/pubmed/31091257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216553
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