Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis

Autophagy is an intracellular catabolic system. It delivers cellular components to lysosomes for degradation and supplies nutrients that promote cell survival under stress conditions. Although much is known regarding starvation-induced autophagy, the regulation of autophagy by cellular energy level...

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Pubblicato in:PLoS One
Autori principali: Che, Lixiao, Yang, Xingyuan, Ge, Chunmin, El-Amouri, Salim S., Wang, Qi-En, Pan, Dao, Herzog, Thomas J., Du, Chunying
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519829/
https://ncbi.nlm.nih.gov/pubmed/31091257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216553
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