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The BRUCE-ATR signaling axis is required for accurate DNA replication and suppression of liver cancer development
Replication fork stability during DNA replication is vital for maintenance of genomic stability and suppression of cancer development in mammals. ATR is a master regulatory kinase that activates the replication stress response to overcome replication barriers. While many downstream effectors of ATR...
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| 出版年: | Hepatology |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541504/ https://ncbi.nlm.nih.gov/pubmed/30693543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30529 |
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