The BRUCE-ATR signaling axis is required for accurate DNA replication and suppression of liver cancer development

Replication fork stability during DNA replication is vital for maintenance of genomic stability and suppression of cancer development in mammals. ATR is a master regulatory kinase that activates the replication stress response to overcome replication barriers. While many downstream effectors of ATR...

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Publicat a:Hepatology
Autors principals: Ge, Chunmin, Vilfranc, Chrystelle L., Che, Lixiao, Pandita, Raj K., Hambarde, Shashank, Andreassen, Paul R., Niu, Liang, Olowokure, Olugbenga, Shah, Shimul, Waltz, Susan E., Zou, Lee, Wang, Jiang, Pandita, Tej K., Du, Chunying
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541504/
https://ncbi.nlm.nih.gov/pubmed/30693543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30529
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