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BRUCE preserves genomic stability in the male germline of mice

BRUCE is a DNA damage response protein that promotes the activation of ATM and ATR for homologous recombination (HR) repair in somatic cells, making BRUCE a key protector of genomic stability. Preservation of genomic stability in the germline is essential for the maintenance of species. Here, we sho...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Che, Lixiao, Alavattam, Kris G., Stambrook, Peter J., Namekawa, Satoshi H., Du, Chunying
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370219/
https://ncbi.nlm.nih.gov/pubmed/32139899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0513-4
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