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Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline

Repressive H3K27me3 and active H3K4me2/3 together form bivalent chromatin domains, molecular hallmarks of developmental potential. In the male germline, these domains are thought to persist into sperm to establish totipotency in the next generation. However, it remains unknown how H3K27me3 is establ...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Maezawa, So, Hasegawa, Kazuteru, Yukawa, Masashi, Kubo, Naoki, Sakashita, Akihiko, Alavattam, Kris G., Sin, Ho-Su, Kartashov, Andrey V., Sasaki, Hiroyuki, Barski, Artem, Namekawa, Satoshi H.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949012/
https://ncbi.nlm.nih.gov/pubmed/29686098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804512115
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