SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination

Gametogenesis is dependent on the expression of germline-specific genes. However, it remains unknown how the germline epigenome is distinctly established from that of somatic lineages. Here we show that genes commonly expressed in somatic lineages and spermatogenesis-progenitor cells undergo repress...

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Publicado en:Dev Cell
Autores principales: Hasegawa, Kazuteru, Sin, Ho-Su, Maezawa, So, Broering, Tyler J., Kartashov, Andrey V., Alavattam, Kris G., Ichijima, Yosuke, Zhang, Fan, Bacon, W. Clark, Greis, Kenneth D., Andreassen, Paul R., Barski, Artem, Namekawa, Satoshi H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391279/
https://ncbi.nlm.nih.gov/pubmed/25703348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.01.014
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