NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy

Recent studies have shown that epigenetic alterations lead to oncogenic activation, thus indicating that these are therapeutic targets. Herein, we analyzed the efficacy and therapeutic potential of our developed histone lysine demethylase 1 (LSD1) inhibitor, NCL1, in castration-resistant prostate ca...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Etani, Toshiki, Naiki, Taku, Naiki-Ito, Aya, Suzuki, Takayoshi, Iida, Keitaro, Nozaki, Satoshi, Kato, Hiroyuki, Nagayasu, Yuko, Suzuki, Shugo, Kawai, Noriyasu, Yasui, Takahiro, Takahashi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517972/
https://ncbi.nlm.nih.gov/pubmed/30935141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8040442
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