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NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy

Recent studies have shown that epigenetic alterations lead to oncogenic activation, thus indicating that these are therapeutic targets. Herein, we analyzed the efficacy and therapeutic potential of our developed histone lysine demethylase 1 (LSD1) inhibitor, NCL1, in castration-resistant prostate ca...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Etani, Toshiki, Naiki, Taku, Naiki-Ito, Aya, Suzuki, Takayoshi, Iida, Keitaro, Nozaki, Satoshi, Kato, Hiroyuki, Nagayasu, Yuko, Suzuki, Shugo, Kawai, Noriyasu, Yasui, Takahiro, Takahashi, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517972/
https://ncbi.nlm.nih.gov/pubmed/30935141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8040442
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