NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy

Recent studies have shown that epigenetic alterations lead to oncogenic activation, thus indicating that these are therapeutic targets. Herein, we analyzed the efficacy and therapeutic potential of our developed histone lysine demethylase 1 (LSD1) inhibitor, NCL1, in castration-resistant prostate ca...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Etani, Toshiki, Naiki, Taku, Naiki-Ito, Aya, Suzuki, Takayoshi, Iida, Keitaro, Nozaki, Satoshi, Kato, Hiroyuki, Nagayasu, Yuko, Suzuki, Shugo, Kawai, Noriyasu, Yasui, Takahiro, Takahashi, Satoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517972/
https://ncbi.nlm.nih.gov/pubmed/30935141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8040442
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