Selective lysine‐specific demethylase 1 inhibitor, NCL1, could cause testicular toxicity via the regulation of apoptosis

BACKGROUND: Recent studies have shown that epigenetic alterations, such as those involving lysine‐specific demethylase 1 (LSD1), lead to oncogenic activation and highlight such alterations as therapeutic targets. However, studies evaluating the effect of LSD1 inhibitors on male fertility are lacking...

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Detalhes bibliográficos
Publicado no:Andrology
Main Authors: Nozaki, Satoshi, Naiki, Taku, Naiki‐Ito, Aya, Iwatsuki, Shoichiro, Takeda, Tomoki, Etani, Toshiki, Nagai, Takashi, Iida, Keitaro, Kato, Hiroyuki, Suzuki, Takayoshi, Takahashi, Satoru, Umemoto, Yukihiro, Yasui, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689788/
https://ncbi.nlm.nih.gov/pubmed/32598553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.12846
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