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Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival
Lysosomes are ubiquitous acidified organelles that degrade intracellular and extracellular material trafficked via multiple pathways. Lysosomes also sense cellular nutrient levels to regulate target of rapamycin (TOR) kinase, a signaling enzyme that drives growth and suppresses activity of the MiT/T...
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| Vydáno v: | PLoS Biol |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516633/ https://ncbi.nlm.nih.gov/pubmed/31086360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000245 |
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