Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

Lysosomes are ubiquitous acidified organelles that degrade intracellular and extracellular material trafficked via multiple pathways. Lysosomes also sense cellular nutrient levels to regulate target of rapamycin (TOR) kinase, a signaling enzyme that drives growth and suppresses activity of the MiT/T...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Biol
मुख्य लेखकों: Murphy, John T., Liu, Haiyan, Ma, Xiucui, Shaver, Alex, Egan, Brian M., Oh, Clara, Boyko, Alexander, Mazer, Travis, Ang, Samuel, Khopkar, Rohan, Javaheri, Ali, Kumar, Sandeep, Jiang, Xuntian, Ory, Daniel, Mani, Kartik, Matkovich, Scot J., Kornfeld, Kerry, Diwan, Abhinav
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516633/
https://ncbi.nlm.nih.gov/pubmed/31086360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000245
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