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NMNAT2‐mediated NAD(+) generation is essential for quality control of aged oocytes
Advanced maternal age has been reported to impair oocyte quality; however, the underlying mechanisms remain to be explored. In the present study, we identified the lowered NAD(+) content and decreased expression of NMNAT2 protein in oocytes from old mice. Specific depletion of NMNAT2 in mouse oocyte...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516161/ https://ncbi.nlm.nih.gov/pubmed/30909324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12955 |
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