Loss of TIGAR Induces Oxidative Stress and Meiotic Defects in Oocytes from Obese Mice

Maternal obesity has been reported to impair oocyte quality in mice, however, the underlying mechanisms remain unclear. In the present study, by conducting a comparative proteomic analysis, we identified a reduced expression of TIGAR (TP53-induced glycolysis and apoptosis regulator) protein in ovula...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Wang, Haichao, Cheng, Qing, Li, Xiaoyan, Hu, Feifei, Han, Longsen, Zhang, Hao, Li, Ling, Ge, Juan, Ying, Xiaoyan, Guo, Xuejiang, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030723/
https://ncbi.nlm.nih.gov/pubmed/29776966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000620
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