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Loss of HDAC3 contributes to meiotic defects in aged oocytes

Maternal age‐related decline in oocyte quality is associated with meiotic defects, but the underlying mechanisms remain to be explored. Histone deacetylase 3 (HDAC3) has been shown to govern multiple cellular events via deacetylating diverse substrates. We previously found that HDAC3 could promote m...

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Publicado en:Aging Cell
Autores principales: He, Yongfu, Li, Xiaoyan, Gao, Min, Liu, Honglin, Gu, Ling
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826132/
https://ncbi.nlm.nih.gov/pubmed/31498540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13036
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