Llwytho...

Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice

Both an increase in osteoclast and a decrease in osteoblast numbers contribute to skeletal aging. Markers of cellular senescence, including expression of the cyclin inhibitor p16, increase with aging in several bone cell populations. The elimination of p16‐expressing cells in old mice, using the INK...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Kim, Ha‐Neui, Chang, Jianhui, Iyer, Srividhya, Han, Li, Campisi, Judith, Manolagas, Stavros C., Zhou, Daohong, Almeida, Maria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516158/
https://ncbi.nlm.nih.gov/pubmed/30773784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12923
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