Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults

IMPORTANCE: Mounting evidence suggests that sex differences exist in the pathologic trajectory of Alzheimer disease. Previous literature shows elevated levels of cerebrospinal fluid tau in women compared with men as a function of apolipoprotein E (APOE) ε4 status and β-amyloid (Aβ). What remains unc...

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Gepubliceerd in:JAMA Neurol
Hoofdauteurs: Buckley, Rachel F., Mormino, Elizabeth C., Rabin, Jennifer S., Hohman, Timothy J., Landau, Susan, Hanseeuw, Bernard J., Jacobs, Heidi I. L., Papp, Kathryn V., Amariglio, Rebecca E., Properzi, Michael J., Schultz, Aaron P., Kirn, Dylan, Scott, Matthew R., Hedden, Trey, Farrell, Michelle, Price, Julie, Chhatwal, Jasmeer, Rentz, Dorene M., Villemagne, Victor L., Johnson, Keith A., Sperling, Reisa A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Medical Association 2019
Onderwerpen:
Original Investigation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515599/
https://ncbi.nlm.nih.gov/pubmed/30715078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.4693
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