Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid

We investigated the effect of baseline Aβ, sex, and APOE on longitudinal tau accumulation in cerebrospinal fluid (CSF) in clinically-normal older adults. 239 participants (aged 56–89 years, Clinical Dementia Rating=0) underwent serial CSF collection for Aβ(1–42), total-tau (t-tau) and phospho-tau(18...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Buckley, Rachel F., Mormino, Elizabeth C., Chhatwal, Jasmeer, Schultz, Aaron P., Rabin, Jennifer S., Rentz, Dorene M., Acar, Diler, Properzi, Michael J., Dumurgier, Julien, Jacobs, Heidi, Gomez-Isla, Teresa, Johnson, Keith A., Sperling, Reisa A., Hanseeuw, Bernard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545139/
https://ncbi.nlm.nih.gov/pubmed/30947113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.02.019
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