FDG metabolism associated with tau-amyloid interaction predicts memory decline

OBJECTIVE: To evaluate in normal older adults and preclinical Alzheimer’s disease (AD) the impact of amyloid and regional tauopathy on cerebral glucose metabolism and subsequent memory decline. METHODS: We acquired positron emission tomography using F18 Flortaucipir (tau), C11 Pittsburgh Compound B...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Hanseeuw, Bernard J., Betensky, Rebecca A., Schultz, Aaron P., Papp, Kate V., Mormino, Elizabeth C., Sepulcre, Jorge, Bark, John S., Cosio, Danielle M., LaPoint, Molly, Chhatwal, Jasmeer P., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404378/
https://ncbi.nlm.nih.gov/pubmed/28253546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24910
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