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Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity
Animal studies demonstrate that hyperactive neurons facilitate early accumulation and spread of tau and amyloid-β proteins in the pathological cascade of Alzheimer's disease (AD). Human neuroimaging studies have linked hippocampal hyperactivity to amyloid-β accumulation, apolipoprotein ε4 (APOE...
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| Vydáno v: | J Neurosci |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335746/ https://ncbi.nlm.nih.gov/pubmed/30482786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1397-18.2018 |
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