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Phases of Hyperconnectivity and Hypoconnectivity in the Default Mode and Salience Networks Track with Amyloid and Tau in Clinically Normal Individuals

Alzheimer's disease (AD) is characterized by two hallmark molecular pathologies: amyloid aβ(1–42) and Tau neurofibrillary tangles. To date, studies of functional connectivity MRI (fcMRI) in individuals with preclinical AD have relied on associations with in vivo measures of amyloid pathology. W...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schultz, Aaron P., Chhatwal, Jasmeer P., Hedden, Trey, Mormino, Elizabeth C., Hanseeuw, Bernard J., Sepulcre, Jorge, Huijbers, Willem, LaPoint, Molly, Buckley, Rachel F., Johnson, Keith A., Sperling, Reisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413178/
https://ncbi.nlm.nih.gov/pubmed/28314821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3263-16.2017
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